Switching to JUUL2 matches tobacco abstinence in reducing harmful substance exposure: study
January 16, 2025
A recent study by Juul Labs researchers has revealed that adult smokers who completely switched to using the JUUL2 system achieved reductions in exposure to harmful and potentially harmful constituents (HPHCs) that were comparable to those who abstained entirely from tobacco and nicotine products.
The study, published in the journal Biomarkers, highlights the potential of JUUL2 as a harm reduction tool for smokers unable or unwilling to quit nicotine entirely.
The randomised study involved 89 adult smokers who were divided into three groups: one that switched completely to JUUL2 (using either Virginia Tobacco or Polar Menthol pods), another that continued smoking their usual cigarette brand, and a third that abstained from all tobacco and nicotine products for six days.
While nicotine exposure levels between the JUUL2 group and those continuing cigarette use remained similar, participants who switched to JUUL2 showed substantial reductions in exposure to HPHCs. Median reductions in biomarkers of exposure (BOEs) to non-nicotine HPHCs ranged from 65 per cent to 94 per cent – a statistically significant improvement compared to those who continued smoking cigarettes.
Interestingly, the reductions in non-nicotine BOEs among the JUUL2 group were comparable to those observed in participants who abstained completely from tobacco and nicotine products.
The findings suggest that adult smokers who fully transition to using JUUL2 system can significantly decrease their exposure to harmful substances found in combustible cigarettes, potentially reducing their risk of smoking-related diseases.
The study adds to the growing body of evidence supporting the role of electronic nicotine delivery systems products in tobacco harm reduction strategies, emphasising the importance of complete transition from smoking to achieve these benefits.
JUUL2 was launched in April 2022 following a successful pilot launch on Juul.co.uk. The rechargeable pod-based system was updated from previous versions with new technologies and features, including the capability to combat potentially harmful and compatible pods, striking a blow to the illicit trade market of JUUL products.
